I had the same problem last year and I contacted both the department head and the professors directly and was actually not granted a prereq. waiver for Bio 2C03, and am now having to take it in 3rd year which is a pain because its a prereq for several 3rd year courses...
that being said, it may be worth a try because this year they are running the course both 1st and 2nd term, and i guess that opens up more spots
i did, however, manage to get a waiver for chem 2OA3, also a course that requires you to be in an honours program, so it is possible to do it.
says thanks to anubhagat for this post.